Active substance: Amitriptyline

Dosage: 50 mg, 25 mg

Price: €26.64 – €97.48

Amitriptyline is a tricyclic antidepressant that increases the activity of brain chemicals (serotonin, norepinephrine), helping to cope with depressive states and improve a person’s well-being and mood. You can buy Amitriptyline without prescription from our online pharmacy. The lowest price in United Kingdom, guaranteed quality and fast delivery – this is what has already attracted more than a million customers to our service!

Where To Buy Amitriptyline In United Kingdom

We offer you the possibility to buy Amitriptyline from our online pharmacy, because we value your time and convenience, so ordering with us is very easy: fill in an order form and we will quickly send it to the place of your choice.

Amitriptyline Without Prescription Online Pharmacy

You can always get medicines without prescription by ordering them from our online pharmacy. You can consult your doctor and not waste time looking for the right medicine.

Affordable Drug Price

You can’t skimp on health, but we have made sure that the price of medicines is the best in the country. In our pharmacy you can buy quality medicines at low prices, and when you order two units in one order there are good discounts.


Thanks to our service, you have the possibility to order anonymously and securely by choosing cash on delivery. Timely delivery to the most convenient distribution point allows you to start treatment as soon as possible.

What is Amitriptyline

Amitriptyline is a tricyclic antidepressant available in 25 mg and 50 mg tablets. The main active ingredient, Amitriptyline, has thymoleptic, antidepressant, anxiolytic, sedative and antidyssuric effects. Amitriptyline is used to treat depression in children and adults.


Amitriptyline is prescribed for:

  • the depressive phase of manic-depressive psychosis;
  • all types of endogenous depression
  • involutional depression
  • depressive syndrome in schizophrenic psychosis
  • depression with organic brain damage
  • depression after prolonged treatment with neuroleptics, reserpine;
  • reactive depression;
  • neurotic depression;
  • enuresis;
  • irritation of the colon;
  • depression in childhood, accompanied by increased anxiety, fear of others;
  • increased anxiety.

Directions for use and posology

The tablets should be taken whole with water. The initial daily dose is 25-50 mg before bedtime. Thereafter, the dose is gradually increased over a week to 150-200 mg daily, divided into several doses, but most are still taken in the evening. If there is no improvement during the second week, the daily dose is increased to 300 mg, and then gradually reduced to 50-100 mg daily.

Therapy should be continued until the symptoms of depression disappear completely, usually for at least three months.

In the elderly or those with mild forms of depression: 50-100 mg daily, taken once before bedtime.

The therapeutic effect of the medicinal product becomes apparent 7-10 days after starting treatment. It is not recommended to take the preparation for more than 6-8 months.


Do not prescribe treatment with Amitriptyline in the following cases:

  • hypersensitivity to the components of the medicinal product
  • concomitant treatment with MAO inhibitors or if taken less than 14 days after discontinuation of the medicinal product
  • paralytic intestinal obstruction
  • glaucoma
  • epilepsy;
  • paroxysmal tachycardia;
  • pregnancy and lactation
  • children under six years of age;
  • pylorostenosis;
  • bladder atony;
  • coronary artery disease;
  • decompensated heart failure;
  • peptic ulcer of stomach and duodenum;
  • prostatic hypertrophy.

Side effects

Possible side effects: dry mouth sensation, dilated pupils, altered accommodation, urinary retention, arrhythmia, paraesthesia, dizziness, dizziness, allergic reactions, tremor of the upper extremities, drowsiness. Side effects are usually not pronounced and do not require discontinuation of the drug, but the patient should be warned of their possible occurrence.

Special Indications

Patients under treatment should refrain from all potentially hazardous activities requiring increased vigilance and rapid reaction. Alcohol consumption is prohibited during the treatment period.

Treatment should be considered ineffective if the patient’s condition does not improve after 3 weeks. The combination of Amitriptyline and nortriptyline may accelerate the antidepressant effect. If treatment is stopped abruptly, a withdrawal syndrome may occur.

How many times a day should Amitriptyline be taken?

At the start of treatment, or if a low dose is given, Amitriptyline tablets should be taken once a day, in the evening. If a high dose is prescribed, it is divided into several doses, but most should be taken before bedtime.

When Amitriptyline takes effect

The therapeutic effect occurs 7 to 10 days after the start of treatment.

How many days should Amitriptyline be taken?
It should be taken until the symptoms of depression disappear, usually for at least 3 months. The maximum duration of treatment is 6-8 months.

What Not to Eat

There are no special dietary requirements during treatment, but alcohol should not be consumed.

Before or After Meals

It is preferable to take it in the evening, before going to bed. The tablet should not be chewed, but taken whole.


Side effects may be increased. Acute poisoning with the drug is life-threatening, seizures and severe impairment of vital functions may occur. Signs of severe cardiotoxic effects may appear 3-5 days after taking an overdose of the drug.

In case of overdose, gastric lavage and the use of activated charcoal are indicated. In case of cardiac abnormalities, ECG monitoring and symptomatic treatment is indicated, without the use of digoxin or β-adrenoceptor blockers.