Colchicine

Do you suffer from gout? Oh, the incredible pain in your joints when you have another attack! Colchicine, a British drug long used to treat gout, can help stabilise the disease, relieve pain and reduce inflammation. Our material will explain in detail how to use this medicine, for whom it is indicated and what are its possible side effects. You will discover the answers to all the most frequently asked questions and concerns and, most importantly, where to buy Colchicine at the best price and without a prescription. Interested? Then go ahead and get the information you need!

Where to buy colchicine in United Kingdom

In principle, you can buy colchicine from any pharmacy that stocks it. But don’t forget that, at the very least, you will have to go to the pharmacy during opening hours and queue among coughing and sneezing people. We, on the other hand, offer you a much more pleasant option: order the medicine without leaving your home and place your order online on our website in a couple of minutes.

Can I buy Colchicine without a prescription from an online pharmacy?

In our pharmacy you can buy the medicine without prescription and pick it up at the nearest post office or the courier will deliver it directly to your home.

Affordable Price

We, like you, love good shopping, but at affordable prices. Before we start, we thought: how can we offer our customers good service and high quality products, but at the same time at the most reasonable prices? The answer is simple: direct delivery of medicines from the warehouses of official medicine manufacturers. We do not spend money on renting additional premises for pharmacies and warehouses, and you get in our pharmacy, in addition to excellent prices, additional bonuses and discounts.

Anonymity

In today’s world, we are all concerned about the security of our data. We would like to buy many medicines anonymously. Our pharmacy is always on the customer’s side, which is why we specify cash on delivery on the order form. It is safe and anonymous. And the fast delivery will be another good advantage for you.

What is Colchicine

Colchicine has a strong anti-inflammatory effect and is widely used for gout, especially in acute attacks (a chronic inflammatory disease of the joints with periodic attacks of acute pain, associated with the deposition of uric acid salts that crystallise in the tissues and cause joint damage in gout).

The drug inhibits the formation of leukotriene B4. It reduces the migration of leukocytes to the inflamed area, inhibits phagocytosis of uric acid microcrystals and prevents their deposition in tissues.

Indications for use of Colchicine

In addition to the treatment of acute attacks of gout, it is also used for the prevention of recurrences of acute attacks of gout, especially in the first 2 years after starting treatment with hippuric agents.

It is also used in:

• Systemic scleroderma (autoimmune disease of connective tissue, with characteristic skin, vascular, musculoskeletal and internal organ involvement, based on microcirculatory disturbances, inflammation and generalised fibrosis);
• Amyloidosis (a disease associated with the deposition of amyloid proteins in tissues and organs, followed by tissue necrosis);
• Behçet’s disease (chronic recurrent multisystemic vasculitis with mucosal inflammation);
• Familial Mediterranean fever (hereditary disease characterised by fever and occasional abdominal pain or occurrence of chest and joint pain or rash).
• chondrocalcinosis (a disease in which changes in the joints gradually develop due to deposits of potassium pyrophosphate salts in the articular cartilage).
• Phlebitis (inflammatory disease of venous vessels, acute or chronic);
• Inflammatory diseases in dentistry.

Contraindications to the use of colchicine

Colchicine should not be used in the presence of the following diseases and allergic reactions:

• Hypersensitivity to colchicine or other components of the drug;
• Hepatic or renal insufficiency;
• severe gastrointestinal disorders
• bone marrow disorders
• neutropenia
• severe myocardiovascular disease
• infections of purulent nature;
• pregnancy and lactation.

The medicine is not recommended for children under 5 years of age.
Before starting treatment, consult your doctor and inform him/her of any illnesses and medications you are taking in order to determine the correct treatment regimen and dosage of the drug.

Side effects of Colchicine

Like all medicines and due to various circumstances, colchicine may not be fully tolerated by all patients. Some adverse reactions have occurred: nausea, vomiting, diarrhoea, malabsorption syndrome, renal and/or hepatic disorders, peripheral neuritis, anorexia, neuropathy, depression, rash, urticaria, leucopenia, thrombocytopenia, azoospermia, transient alopecia.

If side effects occur, consult a doctor; in severe cases, seek emergency medical attention immediately.

Instructions for Use and Dosage

Always consult your doctor before starting to use the medicine. Your doctor will prescribe a treatment regimen and an individual daily dosage of the medicine, which may differ from the doses given below.

The tablets are taken by mouth with plenty of water.
During an acute attack of gout, first take 2 tablets (1 mg) and then 0.5-1.5 mg every 1-2 hours until the pain subsides. The total dose taken in one day should not exceed 8 mg. Repeated administration according to the treatment schedule of an acute attack of gout may be done not earlier than 3 days.

For the prevention of acute gouty arthritis, the medicine is usually prescribed at a dose of 0.5-1 mg per day in the evening.

Take the medicine only in the prescribed dose, as an overdose can be fatal.

Frequently Asked Questions

Below are the most frequently asked questions about the use of colchicine. We have tried to answer the most relevant ones.

How many times a day should colchicine be taken?

It all depends on the diagnosis and the severity of the disease. Generally, the medicine is taken once or twice a day.

When does it start to work?

It is observed that more than 75% of people taking colchicine achieve significant improvement within 12 hours of taking it. It starts to work within 12 to 48 hours of taking it.

How Long Should Colchicine Be Taken?

Only your doctor can answer this question with certainty after a thorough examination and accurate diagnosis.

What Foods Should Be Avoided When Taking Colchicine?

Warning: Excessive consumption of grapefruit juice (1 litre or more per day) can cause a sharp rise in serum colchicine levels, which can be life-threatening.

Medication Taken Before or After Meals

The tablets should be taken independently of meals.

What time of day should colchicine be taken?

It is advisable to take it in the evening.

Colchicine And Alcohol

Alcohol or other medicines containing large amounts of alcohol should not be taken during treatment.