Active substance: Esomeprazole

Dosage: 20 mg, 40 mg

Price: €39.96 – €148.66

Gastro-oesophageal reflux disease is a chronic condition that occurs because the muscular valve in the oesophagus malfunctions, causing stomach contents to back up into the oesophagus. It can lead to reflux oesophagitis, i.e. inflammation of the oesophageal lining and other disturbances. If left untreated, it can lead to destruction of the oesophageal mucosa, which in turn causes inflammation and surface erosion and, in severe cases, ulcerative defects of the oesophagus, sometimes even narrowing. Proton pump inhibitors are used to reduce the acidity of gastric juices.

One such drug is Nexium, which is effective in reducing acid secretion from the stomach by a specific mechanism of action. It is a specific inhibitor of the proton pump in the parietal cells. You will find more information about the properties and action of this drug in our material. We will answer all common questions about the drug in detail, including how to use it and where to buy it at the best price and without a prescription.

Where To Buy Nexium In United Kingdom

The drug can be bought in any pharmacy with a prescription in UK. Of course, you will have to stick to the pharmacy’s opening hours, queue with people sneezing, and the pharmacist may eventually tell you that the drug you want is out of stock. If this is not the case for you, it is time to order your medicine online on our website. And you can do it directly from the comfort of your home or office: a few clicks and your order will be placed and delivered in the shortest possible time.

Can I order Nexium without a prescription from an online pharmacy?

It is likely that in other pharmacies you will encounter the problem that they only sell the medicine on prescription. You will want to come back to our online pharmacy again and again, because in addition to the convenient and fast ordering of medicines, we are always happy to give you the option to buy a medicine without a prescription and have it delivered to the address you give us in any, even the most remote city in United Kingdom.

Affordable Product Price

We know that the cost of medication is as important to you as it is to us. That’s why we are always ready to offer you the best price. The more packages you buy, the more reasonable the price will be. We are also happy to offer you special bonuses and discounts. You may be wondering why everything is so cheap. Simple, our direct contracts with official drug manufacturers and direct deliveries from their warehouses allow us to save a lot compared to traditional high street pharmacies, and this is reflected in the prices for our valued customers.


Anonymity is exactly what our customers are interested in. We are always ready to provide you with what you want. All you have to do is indicate on the online order form the cash on delivery option. It’s safe, anonymous and convenient.

What is Nexium

Nexium is an effective medicine whose active ingredient is esomeprazole, the S-isomer of omeprazole, which reduces the secretion of hydrochloric acid in the stomach by inhibiting the proton pump specifically in the parietal cells of the stomach.


The product has a broad spectrum of activity and is therefore indicated for the following conditions and diseases.

Gastro-oesophageal reflux disease (GORD):

  • Treatment of erosive reflux oesophagitis;
  • long-term treatment of patients with healed oesophagitis to prevent relapse;
  • symptomatic treatment of GERD.

In combination with appropriate antibacterial drugs for the eradication of Helicobacter pylori:

  • Treatment of duodenal ulcer caused by Helicobacter pylori;
  • Prevention of peptic ulcer recurrences in patients with Helicobacter pylori ulcers.

Long-term use of non-steroidal anti-inflammatory drugs:

  • Healing of gastric ulcers due to the use of non-steroidal anti-inflammatory drugs;
  • Prevention of gastric and duodenal ulcers due to the use of NSAIDs in patients at risk.
  • Treatment of Zollinger-Ellison syndrome.

It is also indicated in children from 12 years of age for the treatment of erosive reflux oesophagitis, for the long-term treatment of patients with cured oesophagitis to prevent relapse, for the symptomatic treatment of GORD, in combination with antibiotics in the treatment of duodenal ulcers caused by Helicobacter pylori.

Contraindications for use

Contraindications to the administration of the preparation include hypersensitivity to the active substance or to other components of the preparation, renal and/or hepatic insufficiency, pregnancy, lactation, age below 12 years, hereditary fructose intolerance, glucose-galactose malabsorption or sugar-isomaltase deficiency. Please note that esomeprazole should not be used concomitantly with nelfinavir.
Before taking the medicine, it is advisable to seek advice from your doctor and inform him/her of any medical conditions and medications you are taking. This will prevent you from taking incompatible medicines at the same time.

Side effects

The most common side effects of taking the drug are headache, constipation, abdominal pain, diarrhoea, flatulence, nausea and vomiting. Less frequently, patients have complained of dermatitis, itching, rash, urticaria, alopecia, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, muscle weakness, dizziness, paraesthesia, drowsiness, insomnia, depression, agitation and aggressive behaviour. This is not a complete list of possible side effects. In case of adverse reactions, consult a doctor.

Modalities Of Intake And Dosage

Before starting treatment, consult your doctor, who will decide on your individual regimen and the dosage required.
Tablets should be taken 30 minutes before a meal, swallowed whole and washed down with liquids.

Adults and children from 12 years of age

For the treatment of gastro-oesophageal reflux disease
Treatment of erosive reflux oesophagitis: 40 mg once daily for 4 weeks. Depending on the condition, an additional 4-week treatment is recommended in cases where oesophagitis is not cured or symptoms persist after the first treatment. Long-term maintenance treatment after healing of erosive reflux oesophagitis to prevent recurrence: 20 mg once daily.

In the treatment of gastric and duodenal ulcers

As part of combination therapy for the eradication of Helicobacter pylori: treatment of duodenal ulcer associated with Helicobacter pylori: Nexium 20 mg, amoxicillin 1 g and clarithromycin 500 mg. All drugs are taken twice daily for 1 week.

Patients taking NSAIDs long-term: cure and prophylaxis of gastric ulcers associated with taking NSAIDs: 20 mg or 40 mg once daily. Duration of treatment is 4-8 weeks.

Conditions associated with pathological hypersecretion of the gastric glands, including Zollinger-Ellison syndrome and idiopathic hypersecretion: the recommended initial dose is 40 mg twice daily. Subsequently, the dose is adjusted individually and the duration of treatment is determined according to the clinical picture of the disease.

Frequently Asked Questions

Below you will find the most frequently asked questions about the use of Nexium: how many days should you take it, at what time of day, before or after meals.

How many times a day should Nexium be taken?

In most cases, the medicine is taken once or twice a day. It all depends on the diagnosis and the patient’s condition. The doctor will prescribe a treatment regimen after performing the necessary diagnostic manipulations.

How many days can the medicine be taken?

The medication should be taken strictly according to the doctor’s instructions.

When does it start to work?

The effects of esomeprazole develop within one hour of taking 20 mg or 40 mg orally. If taken daily for 5 days at a dose of 20 mg once daily, the average peak hydrochloric acid concentration is reduced by 90% after stimulation with pentagastrin.

When to Take the Medicine: Before or After Meals

The medicine should be taken 30 minutes before meals.