Active substance: Bisoprolol

Dosage: 10 mg, 5 mg, 2.5 mg

Price: €25.49 – €97.76

Zebeta is a highly effective drug for the treatment of cardiovascular diseases, with a long-standing reputation. In particular, it is used in the treatment of heart failure, coronary heart disease, high blood pressure and heart rhythm disorders.

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What is Zebeta

Zebeta tablets contain the active substance bisoprolol, a well-known β-adrenoblocker drug.

Bisoprolol is widely used in cardiology practice and in some countries is included in the list of the most important medicines for public health.

Indications For Zebeta

  • Coronary artery disease (angina pectoris).
  • Arrhythmia.
  • High blood pressure.
  • Used as part of a complex therapy to treat chronic heart failure.

Zebeta Posology

The dosage regimen and frequency of administration are determined by the treating physician.
The starting dose is always minimal.

The recommended dose for hypertension is 5 mg of Zebeta once daily. The daily dose can be increased to 10 mg per day in two doses. The maximum daily dose is 20 mg.

For the treatment of heart failure, stenocardia, arrhythmia and other diseases, the dose is adjusted according to the severity of the disease, the contraction of the heart muscle and the general condition of the patient.

Zebeta Usage

Zebeta tablets should be taken once daily in the morning. The tablets should be swallowed with a small amount of liquid and should not be chewed. They can also be taken with food.

Zebeta should not be stopped abruptly. Discontinuation should be gradual and the dose should be adjusted downwards.


  • Children under 18 years of age.
  • Hypersensitivity to bisoprolol or to any of the excipients contained in the tablets.
  • Acute heart failure.
  • Cardiogenic shock;
  • Grade II or III atrioventricular block.
  • Sinus node weakness syndrome.
  • Sinoatrial block.
  • Symptomatic bradycardia.
  • Arterial hypotension.
  • Severe bronchial asthma or chronic obstructive pulmonary disease.
  • Severe forms of occlusive disorders of the peripheral circulation, Raynaud’s disease.
  • Pheochromocytoma;
  • Metabolic acidosis.

Zebeta should be used with great caution during pregnancy.

Side effects

Side effects affecting the central nervous system such as dizziness, headache, fatigue and other symptoms may occur during the first few days of taking the drug.

Symptoms such as diarrhoea, nausea, skin rash, respiratory distress, muscle weakness, orthostatic hypotension, bradycardia, etc. may also occur.

Continuous monitoring for hypoglycaemia is required when taking Zebeta in the presence of type 1 and type 2 diabetes mellitus.