Active substance: Lisinopril

Dosage: 10 mg, 5 mg, 2.5 mg

Price: €27.00 – €174.14

Zestril is a very effective medicine for the treatment of high blood pressure. It is well known for use in the first hours after an acute myocardial infarction. It is indicated for long-term use, even in overweight patients.

To buy Zestril in the UK, we recommend that you use the convenient online order form on our online pharmacy website. When ordering, you will be able to choose a convenient pack of medicine at an affordable price, without a prescription. Delivery in Italy is made by a verified postal carrier.

What is Zestril

Zestril tablets contain the active substance Lisinopril, an ACE inhibitor.

Angiotensin-converting enzyme inhibitors (ACE inhibitors) block the effects of a hormone called “angiotensin II”, which is produced naturally by the kidneys.) By blocking the effects of angiotensin II, ACE inhibitors cause the blood vessels to relax, which in turn lowers blood pressure.


High blood pressure.
Diabetic nephropathy.
Chronic heart failure.
Early treatment (within 24 hours) of acute myocardial infarction.


The mode of administration and the dosage of Zestril are adapted to the patient’s condition and the severity of the disease.

The recommended dose for the treatment of hypertension (in the absence of other antihypertensive agents) is 5 mg Zestril once daily.
In the absence of expected effects, the dose is increased every 2-3 days by 5 mg until an average therapeutic dose of 20-40 mg per day is reached.

Dose increases above 40 mg per day do not usually produce further reductions in blood pressure. The usual daily maintenance dose is 20 mg of Zestril. The maximum daily dose is 40 mg Zestril.


It should be taken orally with a small amount of water, but not with meals.

When taken in the context of high blood pressure, the full effect of the medicine usually develops 2-4 weeks after the start of treatment. This should be taken into account when increasing the dose. In case of insufficient clinical effect, Zestril may be combined with other medicinal products.


Zestril is contraindicated during pregnancy.

Other contraindications are: angioedema; hereditary Quincke’s oedema; childhood and adolescence under 18 years; hypersensitivity to the components of the medicinal product; galactose intolerance, lactase deficiency, glucose-galactose malabsorption.

Side effects

The most frequent side effects are headache, dizziness, diarrhoea, weakness, dry cough, chest pain and skin rash.