Active substance: Bupropion

Dosage: 150 mg

Price: €35.99 – €172.75

Antidepressants are widely used in treatment and are prescribed by specialists for a wide variety of symptoms and illnesses. Zyban is used to treat depression and is also used to facilitate the smoking cessation process. You can buy Zyban at the lowest price in the UK from our online pharmacy with fast delivery nationwide. We trust our customers and ship the medicine over the counter and also cash on delivery, so you can start your treatment as soon as possible.

Where To Buy Zyban In United Kingdom

You can buy the product quickly and easily from our online pharmacy. How do I place my order? It’s very simple: fill in the online order form and wait for the delivery notification at your nearest collection point. The site offers a wide range of products, with guaranteed quality and good discounts.

Zyban No Prescription Online Pharmacy

You can order any medicine with guaranteed quality and receive it at the distribution point without a prescription. This saves time, the important thing is to consult the treatment with experts.

Affordable Drug Price

With us you can always buy medicines at an advantageous price. Although our online pharmacy is cheap, high quality products are guaranteed. The prices of all medicines on our site are much lower than in the pharmacy!


Our customers’ orders are always anonymous and secure. We do not disclose your confidential data, including order items, and you can always choose to pay cash on delivery. Fast delivery saves time and allows you to start treatment as soon as possible.

What is Zyban

Zyban is indicated for the treatment of depression and to help nicotine-dependent patients stop smoking. It is available as an extended-release tablet with a dose of 150 mg. The main active ingredient, bupropion hydrochloride, is a psychoanalytic.

Its mechanism of action is selective inhibition of norepinephrine and dopamine reuptake, with minimal inhibition of serotonin reuptake. It also acts as a nicotinic receptor antagonist.


Zyban is used in the treatment of depressive disorders and to facilitate abstinence from tobacco in nicotine-dependent patients.

Dosage and Administration

The tablets should be taken whole, without chewing or crushing, to avoid the risk of cramping. An initial dose of 150 mg once daily should be taken in the morning. If the treatment is not effective, the dose can be increased to 300 mg once daily. The maximum dose of 450 mg daily is prescribed for patients who have not improved after several treatments with a daily dose of 300 mg.

Severe depression requires treatment with bupropion for 6 months or longer after therapeutic effect has been achieved. The dose should be increased and decreased gradually, not more than 100 mg daily. The interval between doses of Zyban should be at least 24 hours.


Zyban should not be used in case of hypersensitivity to any of the ingredients, in children under 18 years of age, in case of seizure disorders, in case of abrupt withdrawal of alcohol or sedatives. Bupropion should not be combined with monoamine oxidase inhibitors and at least two weeks should elapse before discontinuation.

Side effects

Classification of adverse reactions in the body during therapy:
Immune system: urticaria, angioneurotic oedema, bronchospasm, anaphylactic shock, arthralgia, myalgia, fever accompanied by rash.

Metabolism: anorexia, weight loss, changes in blood glucose levels.
Mentality and behaviour: insomnia, depression, restlessness, irritability, aggressiveness, nightmares and dreams.

Nervous system: dizziness, headache, tremors, altered taste, convulsions, loss of concentration, memory loss, fainting, paraesthesia.

Cardiovascular system: increased blood pressure, palpitations, tachycardia, orthostatic hypotension.

Digestive system: nausea, vomiting, constipation, diarrhoea, jaundice, hepatitis.
Other: tinnitus, decreased vision, skin rash, pruritus, increased sweating, fever, chest pain, urinary disorders.

Use During Pregnancy

The safety of bupropion treatment in pregnant women has not been established; it should only be prescribed if the expected benefits outweigh the possible risks. It is advisable to discontinue breast-feeding during treatment because bupropion and its metabolites tend to pass into breast milk.


Drowsiness, arrhythmia and unconsciousness have been reported in cases of bupropion overdose. There is no known specific antidote for bupropion. If the dose is exceeded, the patient should be admitted to hospital, airway controlled and ventilated. Activated charcoal may be used and further treatment should be based on severity of condition and symptoms.

Drug Interactions

Caution should be exercised when using bupropion concomitantly with orphenadrine, cyclophosphamide, ifosfamide, ticlopidine and clopidogrel. Treatment should also be initiated when a minimum dose of antiarrhythmics, antipsychotics, antidepressants, selective inhibitors, levodopa, amantadine is reached.

How many times a day should Zyban be taken?

The tablets should be taken once daily, according to the prescribed dosage, in the morning.

When it starts to work

Onset of action is observed after 1-2 weeks; if there is no improvement, the dose is increased. After improvement, the drug should be taken for at least six months.

How Many Days to Take Zyban

The duration of therapy is determined for each individual patient, for the treatment of major depression at least 6 months after the person’s first improvement.

What Not To Eat During Therapy

Patients should not consume alcohol, cheese, soy sauce, sauerkraut, figs, yoghurt, sultanas, dried fish or meat.

Before or After Meals

The medicine should be taken in the morning with a meal.